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Full writeup by the Australian man who successfully created a custom mRNA vaccine for his dog's cancer

Submitted by the author two days ago [0], but resubmitting here so that it doesn't violate the self-promotion rule.

0 - https://news.ycombinator.com/item?id=47524901


Yeah, but it can be a bit of a tight squeeze if you don't have at least 24gb (preferably 32gb+) of memory.

Especially if you want other apps to run at the same time, I think it's safer to stick with something more like 9b. You can see a table with quantized sizes here [0] -- yes, there are smaller quants than Q4_K_XL, but then you're down in the weeds with nickel-and-diming things, and if you want to even keep something like a (memory-hungry) instance of VSCode running, good luck.

IMO -- if 9b is doing the job, stick with 9b.

0 - https://github.com/ggml-org/LlamaBarn/pull/63


Reminds me of the mainframe in The Moon is a Harsh Mistress.

Nice game!

We made a similar game several years ago for the Pyweek game competition, but there wasn't the fun "letter invaders" style that this one has.

https://pyweek.org/e/RegExExpress/

I really like your implementation!

Might be good to limit some of the special operators to give more focus -- otherwise the early levels are a bit too solvable with ".*"


A judge reviewed the evidence and signed the warrant. It's not like the cops just took what the witness said and ran with it.

I'm amazed at the number of people who are answering "this is just the way that it is in America".

I don't live in Adams County, but they are our direct neighbors here in rural southwest Ohio. We like Afroman over here. :)

I think the answer to your question is the warrant that they were serving involved kidnapping and an alleged torture dungeon along with drug trafficking charges. Yes, it may sound ridiculous on the surface, but an informant apparently testified to this and a judge approved it, so that's the warrant they were serving.

If one reads the warrant and considers the possibility that the testimony of the witness might have been true, then their show of force seems much less unreasonable.

Disconnecting his cameras? Stealing his money? That's absolutely not reasonable in any case. Afroman has a lot of support in our rural Ohio community, and we're all cheering for him. :)


I want to point out that no, the contents of the warrant are in no way “the reason” for this type of raid. It is factually untrue to use that detail to suggest in any way that this is not business as usual in the US.

I cannot stress enough how factually untrue the comment I’m responding to is - it is more of a prayer than a description of the reality of policing in the United States. At best what GP meant to say is that to the best of their knowledge this usually doesn’t happen in the sparsely populated handful of square miles that they’re familiar with in the time that they have lived there and mistakenly given the impression that it is categorically uncommon in the US.

It is business as usual for the entirety of the country, though it’s I guess fun for the locals (?) to see some “torture dungeon” flavor thrown in there by a ‘witness’ that the public will definitely never hear from.

Finding examples of this is trivial. It happens all the time and if Afroman were not famous this would not have risen to the level of national news. It’s even somewhat common for raids like these to happen where they get the address wrong and raid the wrong house.


> I cannot stress enough how factually untrue the comment I’m responding to is

Which fact did I report incorrectly?

I was not answering the question in generalities. I was answering the question that asked for specifics about this case ("why so many drawn guns? Fun music videos aside, what was the background here?"). The answer: serving a warrant for kidnapping and drug trafficking.

You may disagree with my :opinion: (that armed response during the serving of a warrant for kidnapping is reasonable, or that the cops should not have disconnected his cameras), but you can't just claim that I'm lying about the facts of this case and then not bring receipts.


Its not even police specific.

In any game, if one side has 10x more accountability for misbehavior than the other, the low consequence side will keep testing boundaries until they are stopped.


>but an informant apparently testified to this and a judge approved it, so that's the warrant they were serving.

And will they face repercussions for such an obviously false lead? You need a lot more than an "informant" to verify a search warrant. Especially under a local celebrity who has all kinds of people out there who want to harass them.


Sounds like swatting.

"an informant apparently testified to this and a judge approved it" sounds very far away from what I understand "swatting" to mean normally.

AFAIK we have no idea if an informant testified to it, or even if there was an informant. Cops claimed that someone had told them about it, and the judge signed the warrant.

Swatting is the action or practice of making a hoax call in an attempt to bring about the dispatch of a large number of armed police officers to a particular address"

Either there was an informant, and the false claim was made to a police officer, or there was not informant, and the cop made a false claim to the judge. Either way, the intent was to get cops to show up and screw with Afroman, and that goal was achieved.


I agree with you. It might not be "swatting" in the crank call sense, but it definitely feels like malicious lying (on the part of _someone_) to harass or cause injury through police action. So yeah, definitely feels like swatting to me too.

Trigger warning: very stupid question to follow.

To my smooth-brain naiveté, this feels like the sort of thing that we could reward with some sort of cryptocurrency in a blockchain? It's difficult to achieve gains, but it's relatively quick to independently verify (5 minute training runs).

I know "blockchain all the things" is sooooo 8 years ago, but I'm looking at the descending graph of progress here, and wondering if being able to claim improvement tokens (even for no reason other than NFT-esque bragging rights) wouldn't be a cool thing here?

I'm asking this as someone who knows next to nothing about crypto or blockchain or any of those things, but mainly thinking of trying to gamify assigning GPU rigs to "mining" these measurable improvements.


I had this idea in 2019 -- "p2p machine learning" with some sort of incentive.

It makes a lot of sense to incentivize contributing. My idea was that you could earn "credits" for participating, which you could exchange for compute resources from the "swarm" later, on any given problem (training, local inference, etc).


I worked on building blockchains for about 4 years, and this is not a stupid question at all. The verification problem is real. A 5-minute training run produces an objective val_bpb score that anyone can reproduce from the published source code. And this is actually valuable work, unlike most proof of work chain workloads.

The practical challenge is that adding a blockchain means agents also need to participate in consensus, store and sync the ledger, and run the rest of the network infrastructure on top of the actual research. So it needs a unit economic analysis. That said, all results already include full source code and deterministic metrics, so the hard part of verifiable compute is already solved. You could take this further with a zkVM to generate cryptographic proofs that the code produced the claimed score, so nobody needs to re-run anything to verify. Verification becomes checking a proof, not reproducing the compute.

Compute-credits are interesting. Contribute GPU time now, draw on the swarm later for training, inference, whatever you need. That's a real utility token with intrinsic value tied to actual compute, not speculation.


> The verification problem is real. A 5-minute training run produces an objective val_bpb score that anyone can reproduce from the published source code. And this is actually valuable work, unlike most proof of work chain workloads.

Yes, thank you for the validation! That was the core of what sparked this for me -- my cartoon drawing of blockchain is that it's dependent on problems that are difficult to solve (improve this codebase), but easy to verify (loss went down).

Like you noted, this is also cool in that it's valuable work (unlike most of these workloads)

I appreciate the opportunities for optimization you've laid out (such as zkVM) but it feels like that would be optional compared to the basic thing here?

And yeah -- what one _does_ with the crypto-credits is pretty open-ended. Like you said, drawing on the swarm for training or inference or whatever you need -- it feels like the sort of thing that one could use as a GPU battery of sorts. Most of my personal GPU work goes in bursts -- but most of the time my GPU is sitting idle.

Most of the other GPU share-cropping sorts of ideas I've seen floating around lack the ability to independently prove that work was done. Having a global metric for a shared target like this seems to solve what has been lacking in a lot of other distributed systems I've seen.

Looking at the graph on the website, it looks like it's already got a bit of a scoreboard and independent verification / validation of results. Feels like it would be a relatively small jump to crowdsource this and put it into a formal blockchain.

But the next natural question is: Would we stand to gain anything by adding blockchain to this?


I appreciate this being added to the guidelines.

That said, I also wouldn't hate seeing an official playground where it is cordoned / appreciated for bots to operate. I.E., like Moltbook, but for HN...? I realize this could be done by a third party, but I wouldn't hate seeing Ycombinator take a stab at it.

Maybe that's too experimental, and that would be better left to third parties to implement (I'm guessing there's already half a dozen vibe-coded implementations of this out there right now) -- it feels more like the sort of thing that could be an interesting (useful?) experiment, rather than something we want to commit to existing in-perpetuity.


You could mirror article postings and upvotes to another site and let AI play around there - if it's interesting to people maybe it will gain a following. I don't see any reason it'd need to happen in this specific forum as that'd likely just cause confusion.

At the time being, at least, HN is a single uncategorized (mostly, lets ignore search) message board - splitting it into two would cause confusion and drastically degrade the UX.


https://news.clanker.ai/

This might be roughly what you're looking for?


I never played it, but from what I've heard, it sounds like the original Star Wars: Galaxies MMO (before they added all the NGE stuff?) had fairly mundane / commoner roles as well.

It sounds like a fan-driven reboot of this game has a fairly decent following, in a very similar way to what UO experiences? It feels like there is still player desire to have mundane sorts of immersive RPG experiences in this way.


Oh this is really cool! Reminds me of ggwave [0].

It feels difficult to create hobbyist peripherals that interface with ones' phone -- trying to get cross-platform credentials to plug your own Arduino in via USB or connect via Bluetooth feels like a chore. I like the idea of phones communicating via some sort of audio library (ultrasonic maybe?) -- like R2-D2 chirping back and forth to communicate with other droids. I think this sort of thing could be part of a nice network of cross-device communication.

[0] - https://github.com/ggerganov/ggwave


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