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> The other reason the author misses - the internet was a much smaller place. A personal website or forum would be seen by a large percentage of the internet. The "indie" web was the web. (Drop the "indie".) Now you have to go live on a platform and be an ephemeral engagement sink.

Some of this might just be demographic shifts, i.e. "normal" people using the internet more. The people who are on the internet now would likely never have been interested in reading some indie blog, they just weren't online in 2000.

I could be wrong, but I suspect the absolute number of people who read this blog today is larger than it would have been in 2000, just in a smaller corner of the internet.


It feels like the youngest generation are more enthralled by the big media/tech regime online than we were 20 years ago though

Sure we used AIM and MSN Messenger but we also used IRC, visited forums and looked at newsgroups.

So many people these days don't even own laptops. Their entire digital footprint comes through apps on restrictive mobile platforms.


The editor should have indented that line correctly.


Stress can inhibit neurogenesis (among other things) in the hippocampus, as the article states. Is it possible that HIIT was not as beneficial for the rodents, because they were, unlike the moderate exercisers, forced to exercise? Being forced to exercise intensely might have been the real source of stress.


Having a weight strapped to your tail could definitely be stressful too.


For humans it is different.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772595/ - brain derived neurotrophic factor (BDNF) serum level increase for what can be considered high intensity exercise.

http://www.medscape.com/viewarticle/723059 - resistance training induce BDNF release, from all of the body. BDNF can cross brain-blood barrier.

Rodents are easy to experiment with, but quite distant from humans in actual metabolism.


This struck me as the most important potential difference -- that the moderate-intensity rats were able to make choices about when and how to exercise, while the HIIT rats had exercise forced upon them.

It reminds me of Rat Park -- when you stress out rats by treating them poorly, all you end up measuring is the effect of misery on rat physiology.


The lottery analogy made me think of this: Even if most startups fail, is the expected value nonetheless positive?


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