I recommend Peter Attia's highly engaging and informative talk [0] on the same topic, which I think does a better job at articulating the motivation behind possible approaches to attacking the issue of health- and life-span.
I second this. I think Attia is one of the clearest thinkers on health, longevity and nutrition currently. Moreover, he is a trained doctor AND an ex-McKinsey consultant, a combination that marries a strongly analytical and numerical lens to a field (medicine) that notoriously isn't.
[0] https://www.youtube.com/watch?v=vDFxdkck354