I'm on setraline - a pretty light dose, these days (can't remember it off the top of my head). I've been prescribed a bunch of stuff over the years, and have developed the impression that the prescription process is more art than science. Doctors tend to overprescribe, so you get sledge-hammer style effects. A good psychiatrist will usually prescribe two or more anti-depressants in light doses, so you don't really get side-effects or weird stuff.

Obviously, starting and stopping drugs is always rough, but I have tried living without them, and I see no benefits. You do generally get side-effects to some degree (I have very dry skin at the moment) - but if you have even the most trivial depression, you'll probably find you prefer them to even a light episode. Also, they aren't a silver bullet. I still have depressive days, from time to time - but the difference is, it's not my life anymore. I can hold down jobs, have relationships, etc.