That's very interesting. I hope they find a way to embed it into our natural enamel. I've had problems with sensitive teeth and enamel for years.
I actually found a very interesting toothpaste with a substance that Sensodyne used to sell in the US, but completely abandoned it and now only sell it in the UK. Which is why I order my toothpaste from the UK. It a a very interested compound called NOVAMIN (Calcium Sodium Phosphosilicate) which is a "bioglass"
>NOVAMIN forms a robust hydroxyapatite-like layer over exposed dentin and within exposed dentin tubules
You can read more about it on GSK's website: https://www.gskhealthpartner.com/en-ca/oral-health/brands/se...
It includes the studies that have been done on it. Here's a seller in the UK that's selling a 2 pack for $22. It is a bit pricey, but I do feel it's worth it for the price as my sensitivity has gone down greatly while using it. I use half a strip of Colgate sensitive (as it has potassium nitrate in it, which tells the nerve ends in the dentin to stop firing as that can cause painful sensitivity) and half a strip of Sensodyne w/Novamin. https://amzn.to/3gupUcX
I originally found the stuff through this article on medium called "The curious history of NovaMin toothpaste". Apparently, it might have been originally created to help bone regeneration of injured military personnel & there's kind of a 'conspiracy' as to why it's not sold in the US.
https://medium.com/@ravenstine/the-curious-history-of-novami...
it seems like it works for sensitivity, but not so much for remineralization, but I don't think that that US vs. UK difference is related, it is a FDA issue with more than one active ingredient[0].
In the UK the "new kid on the block" is seemingly Biomin:
Yes, I've read the first study, and it is a review of all the material surrounding Novamin and suggests there should be more research. There should always be more research, but I still contend the research on Novamin is quite solid as is. Other studies have shown it does infer remineralization properties (when compared to fluoride alone).
I have also read about BioMin, but I am a bit skeptical on it. It seems to be more of a "slow release fluoride" that sort of sticks to the teeth and releases the fluoride ions over the day. While Novamin is a true "bioglass" formula. The link you provided to Biomin claims that because Novamin on it's own contains no fluoride and requires the addition of fluoride into the toothpaste I think is a weak one. Biomin appears to be a simple bond of the molecules of calcium, phosphate and fluoride.
Nonetheless, they do have some impressive studies, but I didn't see one where they compared Biomin _directly_ to a formula of Novamin + sodium fluoride or a similar combination of Novamin and fluoride in the same formula, simply comparing Novamin to Biomin - which already contains fluoride. I might give it a try at some point. It's a novel compound.
https://www.biomin.co.uk/professional-information/clinical-s...
According to a short writeup on quora, the claim was made that because the FDA regulates toothpaste as a drug, whereas in Europe it's regulated as cosmetic, GSK would have to prove Novamin had the properties it claimed and would have to go through many clinical trials, as any new drug on the market would be required to do. So, because of the expense of this, they simply pulled it off the US market.
https://www.quora.com/Why-are-there-not-any-toothpastes-with...
Notably in the EU novamin toothpastes don't make any claims as to tooth repair, only as to sensitivity reduction. (for which it hella works in my experience)
I actually found a very interesting toothpaste with a substance that Sensodyne used to sell in the US, but completely abandoned it and now only sell it in the UK. Which is why I order my toothpaste from the UK. It a a very interested compound called NOVAMIN (Calcium Sodium Phosphosilicate) which is a "bioglass"
>NOVAMIN forms a robust hydroxyapatite-like layer over exposed dentin and within exposed dentin tubules You can read more about it on GSK's website: https://www.gskhealthpartner.com/en-ca/oral-health/brands/se... It includes the studies that have been done on it. Here's a seller in the UK that's selling a 2 pack for $22. It is a bit pricey, but I do feel it's worth it for the price as my sensitivity has gone down greatly while using it. I use half a strip of Colgate sensitive (as it has potassium nitrate in it, which tells the nerve ends in the dentin to stop firing as that can cause painful sensitivity) and half a strip of Sensodyne w/Novamin. https://amzn.to/3gupUcX
I originally found the stuff through this article on medium called "The curious history of NovaMin toothpaste". Apparently, it might have been originally created to help bone regeneration of injured military personnel & there's kind of a 'conspiracy' as to why it's not sold in the US. https://medium.com/@ravenstine/the-curious-history-of-novami...