High end estimates of people killed due to the deliberate spread of disease are dozens to hundreds. The pre-real-contact wave was obviously many orders of magnitude more deadly. Even your own link mentions one reason it was ineffective was prior exposure.

the vast majority of indigenous people died on the 1° 100 years of colonization (from 1500 (when America was "found") -> 1600); the number goes up to 80 million people dead... the paper i mentioned says partial immunity didn't taking effect on a war past 1700! do you really think pox wasn't abused the time they were killing millions of natives per year? that's what i'm reffering to, not (somehow) recent wars

Yes, there is no credible evidence of your claim. The big disease waves stuck most natives before they ever saw a European, after contacted peoples caught disease in the normal fashion. The very few later documented attempts we have are almost completely ineffective, and often from people in a very desperate situation (e.g., besieged and dying of smallpox) - just a last ditch gambit that never accomplished its goal.