Firefox 21 and 22 support streaming MP4 in HTML5.
OS X is a bit more complicated due to needing to poke at Quicktime for the codecs.
Still waiting on Opera to make a move for mp4...especially with the promises that H.265 make in regards to reduced file sizes with great qualities.
Although I know mp4 is patent encumbered, it's too prevalent to ignore (thanks to Apple and Microsoft products).
Firefox 21 and 22 support streaming MP4 in HTML5.