Cool! I almost went into a lab studying polyketide synthase enzymes. How heavily do they feature in your pathways? Is their modularity overstated/understated?
(I fully intend to stalk you on google scholar after I get back to the things I really ought to be working on right now...)
Hah! Oh PKS-es! Megasynthases (PKS, NRPS, FAS) do not currently feature very heavily in our algorithms, but their modeling is certainly within our intended algorithmic expansion plans. As for whether they are understated/overstated, my cofounder can sit you down for hours and speak about them, but you have probably moved on!
ps: Googling me will lead you to program synthesis: programs that program programs :) which is another curiosity that you may or may not want to dive into. You will find a lot more biology from my cofounder. google scholar: chris anderson synthetic biology.
(I fully intend to stalk you on google scholar after I get back to the things I really ought to be working on right now...)